64-Channel multi-detector row CT angiographic evaluation of the micropigs for potential living donor lung transplantation.
10.4142/jvs.2010.11.3.185
- Author:
Woong YOON
1
;
Jung Min RYU
;
Min Young LEE
;
Yong Ju MOON
;
Sang Hun LEE
;
Jae Hong PARK
;
Seung Pil YUN
;
Min Woo JANG
;
Sung Su PARK
;
Ho Jae HAN
Author Information
1. College of Veterinary Medicine, Biotherapy Human Resources Center (BK21), Chonnam National University, Gwangju 500-757, Korea. hjhan@chonnam.ac.kr
- Publication Type:Original Article ; Evaluation Studies ; Research Support, Non-U.S. Gov't
- Keywords:
lung;
micropig;
multidetector row computed tomography (MDCT)
- MeSH:
Animals;
Humans;
Lung/physiology/*radiography;
Organ Size/physiology;
Pulmonary Artery/physiology/*radiography;
Swine;
Swine, Miniature/*anatomy & histology;
Tomography, X-Ray Computed/*methods;
Transplantation, Heterologous/*methods
- From:Journal of Veterinary Science
2010;11(3):185-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
Micropigs are the most likely source animals for xenotransplantation. However, an appropriate method for evaluating the lung of micropigs had not been established. Therefore, this study was performed to evaluate the feasibility of 64-channel multi-detector row computed tomography (MDCT) to measure the diameter of the pulmonary arteries and the lung volume in micropigs. The mean diameters of the trachea, and left and right bronchi were 1.6 +/- 0.17, 1.18 +/- 0.14, and 1.1 +/- 0.11 cm, respectively. The mean diameters of the main, right, and left pulmonary arteries were 1.38 +/- 0.09, 1.07 +/- 0.26, and 0.98 +/- 0.13 cm and the diameters of right, left, and common inferior pulmonary veins were 0.97 +/- 0.20, 0.76 +/- 0.20, and 1.99 +/- 0.26 cm, respectively. The mean lung volume was 820.3 +/- 77.11 mL. The data presented in this study suggest that the MDCT may be a noninvasive, rapid, and accurate investigational method for pulmonary anatomy in living lung donors.
