Prostatic Cancer Presenting as an Isolated Large Lung Mass.
10.4046/trd.2010.68.5.290
- Author:
Hee Sun NO
1
;
Jong Hwan LEE
;
Young AHN
;
Im Il NA
;
Hye Ryoun KIM
;
Cheol Hyeon KIM
;
Jae Soo KOH
;
Jae Cheol LEE
Author Information
1. Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea. jclee@kcch.re.kr
- Publication Type:Case Report
- Keywords:
Metastasis;
Prostatic Neoplasms;
Thyroid Transcription Factor 1;
Tumor Markers, Biological
- MeSH:
Adenocarcinoma;
Biopsy, Needle;
Humans;
Lung;
Lung Neoplasms;
Middle Aged;
Neoplasm Metastasis;
Nuclear Proteins;
Prostate-Specific Antigen;
Prostatic Neoplasms;
Thyroid Gland;
Transcription Factors;
Biomarkers, Tumor
- From:Tuberculosis and Respiratory Diseases
2010;68(5):290-293
- CountryRepublic of Korea
- Language:English
-
Abstract:
A hidden primary tumor presenting as an isolated lung mass is a diagnostic challenge to physicians because the diagnosis of lung cancer is likely to be made if the histologic findings are not inconsistent with lung cancer. A large lung mass was found incidentally in a 59-year-old man. Although adenocarcinoma was diagnosed by percutaneous needle biopsy, thyroid transcription factor-1 (TTF-1) immunostaining was negative, raising suspicion that there was another primary site. There was no abnormal finding except for the lung mass on a 18FDG-PET/CT scan and the patient did not complain of any discomfort. Finally, prostatic cancer was confirmed through the study of tumor markers and prostate-specific antigen (PSA) immunostaining. Because of the rare presentation of a single lung mass in malignancies that have another primary site, physicians should carefully review all data before making a final diagnosis of lung cancer.
