Further Recognization of Disease Name in Traditional Chinese Medicine for Knee Osteoarthritis Based on Micropathologic Phenotypes
10.13288/j.11-2166/r.2025.11.001
- VernacularTitle:基于微观病理表型的膝骨关节炎中医学病名再认识
- Author:
Hongfei WU
1
;
Yushi CUI
1
;
Yun GAO
2
;
Shuai ZHANG
1
;
Mingyuan WANG
1
;
Xingping ZHANG
3
;
Zhilong ZHANG
4
Author Information
1. Eye Hospital，China Academy of Chinese Medical Sciences，Beijing，100040
2. Institue of Acupuncture and Moxibustion，China Academy of Chinese Medical Sciences
3. Data Center for Traditional Chinese Medicine，China Academy of Chinese Medical Sciences
4. Wangjing Hospital，China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
knee osteoarthritis;
bi （痹） disease;
disease name in traditional Chinese medicine;
pathological phenotype
- From:
Journal of Traditional Chinese Medicine
2025;66(11):1089-1093
- CountryChina
- Language:Chinese
-
Abstract:
This paper interprets the disease name related to bi （痹） disease in traditional Chinese medicine （TCM） from the perspective of micropathological phenotypes in knee osteoarthritis （KOA）. By systematically reviewing classical TCM literature on the pathogenesis and clinical features of different subtypes such as damp-retention bi， bone bi， and tendon bi， and integrating these with current research on pathological subtypes of KOA including the synovitis type， cartilage-meniscus type， and subchondral bone type， the study explores the correlation between traditional disease terms and modern micropathological phenotypes. The author proposes subtype classifications of damp-retention bi corresponding to synovial inflammation， bone bi related to abnormal subchondral bone remodeling， and tendon bi representing cartilage and meniscus degeneration. This approach provides a microscopic biological explanation for TCM syndrome differentiation and offers new perspectives for advancing integrative diagnostic and therapeutic strategies in both Chinese and western medicine.
