A case report of cerebral malaria combined with cyanotic congenital heart disease in a child and literature review
- Author:
JIN Mei
;
LIANG Juanjuan
;
SHI Lei
;
HE Fengxiao
- Publication Type:Case Reports
- Keywords:
Malaria;
congenital heart disease;
artesunate;
children
- From:
China Tropical Medicine
2024;24(5):624-
- CountryChina
- Language:Chinese
-
Abstract:
Abstract: Malaria is one of the deadliest vector-borne infectious diseases in Africa, seriously endangering human life and health. Among them, cerebral malaria (CM) has a higher morbidity and mortality rate in children, with clinical manifestations primarily involving neurological symptoms, and comprehensive treatment mainly using artemisinin derivatives. When children with cerebral malaria are complicated by congenital heart disease and induce acute hypoxic attacks, the diagnosis and treatment face great difficulties in the absence of effective examination and monitoring treatments. Similar cases have rarely been reported at home and abroad. The paper summarizes and reports a case of a child with cerebral malaria combined with cyanotic congenital heart disease, treated during an aid mission to Africa, who was improved and discharged from the hospital after receiving multidisciplinary anti-malarial, intracranial pressure lowering, neurotrophic and symptomatic supportive treatment. This paper also discusses the diagnosis and treatment process of this child under difficult conditions, combined with current literature reports, in hopes of providing a reference for clinical treatment.
- Full text:202506171724156109222.A case report of cerebral malaria combined with cyanotic congenital heart disease in a child.pdf