Progress in the research of pre-erythrocytic malaria vaccines
- Author:
FANG Qiang
;
CAO Yujie
;
XIA Hui
- Publication Type:Review
- Keywords:
Malaria;
pre-erythrocytic vaccines;
plasmodium
- From:
China Tropical Medicine
2024;24(4):400-
- CountryChina
- Language:Chinese
-
Abstract:
Malaria is a significant global infectious disease that once wreaked havoc in China as well. In recent years, the global malaria control situation has stagnated, and China is also facing a huge threat of imported malaria. So, effective malaria vaccines are urgently needed as a supplementary strategy to the existing prevention and control measures. Compared to vaccines targeting the erythrocytic stage and those designed to block transmission, vaccines aimed at preventing infection during the pre-erythrocytic stage have attracted more attention and have made a series of progress in recent years. At present, the only two malaria vaccines recommended by the World Health Organization (WHO) are pre-erythrocytic vaccines. In this paper, the current situation and trend of pre-erythrocytic malaria vaccine research and development are reviewed, intending to provide a reference for the research, development, and application of malaria vaccines in the future.
- Full text:20250616164350800587.Progress in the research of pre-erythrocytic malaria vaccines.pdf