Antacid Calcium-6 Preparation Study In The Clinical Condition
- VernacularTitle:Эмнэлзүйн Нөхцөлд Антацид Кальци-6 Бэлдмэлийг Судалсан Үр Дүн
- Author:
Alimaa U
1
;
Oyuntsetseg N
1
;
Seesregdorj S
1
Author Information
- Publication Type:Journal Article
- From: Journal of Oriental Medicine 2016;10(1):37-40
- CountryMongolia
- Language:Mongolian
- Abstract: The study goal was to determine efficiency of Antacid calcium-6 preparation to gastro-esophageal reflux disease by clinical study.The material and methods were randomized controlled trial.The study was 2 phased. In the first phase, participants are given Antacid Calcium-6 p.o, and then monitored gastric acidity by pH monitoring for 24 hours. We evaluated how to effect to reflux condition in before and after treatment by DeMeester index, G.A. Agafanova, A.P.Kholopov scores.The results are gastric minimum pH was 4.12±0.4, pH mean of 24 hours was 7.69±0.39, DeMeester index was decreased (p=0.001-0.005). These results are show Antacid calcium-6 decreases gastro-esophageal reflux. After taken preparation gastric pH become 4.62±1.54 was proven this preparation’s effect of to neutralize to gastric acidity. In the second phase, we compared between Antacid calcium-6 and Orgil mineral water by randomized comparative trial’s design and participants are filled GerQ form and performed gastro-esophageal flexible endoscopy in before and after treatment. Antacid calcium group people had changes of esophageal mucosa (88.2%), decreased ulcerative changes (52.9%) and improved gastritis (70%).In the Orgil mineral water group these changes were 63.3%, 33.3%, 29.6%. These results shown antacid calcium-6 is better than orgil mineral water to use treatment of GERD. In conclustion, antacid calcium-6 biological preparation has effect to neutralize enough in gastric acidity, and supports healing process in GERD.
