The Preparation Of Mongolia Shar Gaa Extract And Experimental Research In It’s Inhibition Of Fungus And Bacterium
- VernacularTitle:Шар Гаа Бэлдмэлийн Бактер, Мөөгөнцрийн Эсрэг Үзүүлэх Идэвхийг Судалсан Дүн
- Author:
Bukhtsetseg Ch
1
;
Nomin-Erdene U
1
;
Oldokh S
1
;
Tsend-Ayush D
1
Author Information
1. Mongolian National University Of Medical Sciences
- Publication Type:Journal Article
- Keywords:
Shar gaa;
reaction on bacteria and anti-fungal
- From:
Journal of Oriental Medicine
2014;6(2):37-43
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background: The prescription of Shar gaa made from the Curcuma
longa L., Tribulus terrestris L., Cortex Phellodendri L., Gardenia
jasminoides L. By reviewing a lot of relative research papers and the
pharmacological dictionaries, we summarized the conclusion that the
efficiency components of the Shar gaa extract is effective to control the
infection of bacteria and the fungi, to relieve skin inflammation and
pain.Aim:We conducted the control experiment to discuss thecontrol
effect of the Shar gaa extract to the fungi and the bacteria. Materials
and methods:We carried out susceptibility test to fungus and bacterium
using medicine dilution method and cup-plate method on the sand clan
proof agar culture and nutrient agar culture. The fungi inhibition results
show that the Shar gaa extract has the significant restrain effects to all
of experimental fungi. It has the better effects to the Microsporum
lanosum M.grpseum、T.rubrum、M. canis、C.albicans、Pityrosporum
than the 20% Ethanol control group (P<0.05). Meanwhile, it has the
same affects with the CAILE extract (P>0.05). In addition, the Shar gaa
extract of high concentration has no significant difference with the one
of the low concentration. This phenomenon demonstrated the truth that
the Shar gaa extract has no concentration diversity to inhibit the fungi
(P>0.05). On the other hand, the bacterium inhibition results
demonstrate that the weak restrain effects of the Shar gaa extract.
Regard to the gram positive bacteria (mainly including the S.aureas,
Bacillus anthraci, Staphylococcus), the Shar gaa extract has the less
effect to control the bacteria than the Penicillin group (P<0.05) and to
the gram negative bacteria (the Pseudomonas) the Shar gaa extract
has the less effect to control the bacteria than the Gentamicin group
(P<0.05). Invalid of the drug-resistant E. coli and the P.mirabilis the
Shar gaa extract group. The 20% Ethanol on bacterial group had no
inhibitory effect. Conclusion: The Shar gaa extract possessed
favourable inhibitory effect to frequent fungus and relative weak
inhibitory effect to general bacterium in clinic. The research
achievement not only expanded the new type of the Shar gaa -4 tan,
but also developed the new usage of the Shar gaa-4 tan. It is to have
the potential guide significance to clinical application.
