Effect Of Jamts-4 Tan On Pancreatic Model In Rats
- VernacularTitle:Харханд Үүсгэсэн Панкреатитын Эмгэг Загварт Жамц-4 Тангийн Үзүүлэх Нөлөө
- Author:
Tuya T
1
;
Chimedragchaa Ch
1
;
Alimaa T
1
;
Dejidmaa B
1
Author Information
1. Mongolian National University of Medical Sciences
- Publication Type:Journal Article
- From:
Journal of Oriental Medicine
2013;4(1):81-83
- CountryMongolia
- Language:Mongolian
-
Abstract:
Aim: To study the beneficial effects of Jamts-4 tan in an experimental
pancreatitis model.
Methos: Acute pancreatitis was induced in four groups of rats (n = 10)
by L-arginine 20% solution (450 mg x100g, intraperitoneal single
injected) and 3 days later, they received a single oral dose of Jamts-4
tan (140 mg/kg), Pancreatin (100 mg/kg) and vehicle (distilled water).
A saline (0.9% NaCl) treated group served as a normal control.
Efficacy was assessed determination of serum levels of amylase,
glucose.
Results: Jamts-4 tan treatments significantly (P < 0.009) attenuated
the L-arginine-induced increases in pancreatic wet weight/body
weight ratio, and decreased the serum levels of amylase as
compared to the vehicle control.
Conclusion: Jamts-4 tan has the potential to combat acute
pancreatitis
