Gestational Diabetes Mellitus, Fetal Growth and Vitamin D.
10.11005/jbm.2017.24.3.155
- Author:
Hyun Koo YOON
1
Author Information
1. Department of Internal Medicine, Cheil General Hospital & Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea. hyunkooyoon@hotmail.com
- Publication Type:Review
- Keywords:
Diabetes;
Gestational;
Fetal development;
Vitamin D
- MeSH:
Diabetes Mellitus;
Diabetes, Gestational*;
Female;
Fetal Development;
Glucose;
Hypertension;
Metabolism;
Pregnancy;
Pregnancy Complications;
Receptors, Calcitriol;
Vitamin D Deficiency;
Vitamin D*;
Vitamins*
- From:Journal of Bone Metabolism
2017;24(3):155-159
- CountryRepublic of Korea
- Language:English
-
Abstract:
Vitamin D is an important secosteroid hormone in skeletal and non-skeletal systems. Vitamin D has relevance to muscle and immune function, hypertension, diabetes mellitus, cancer, and pregnancy because vitamin D receptors (VDR) are present in many non-skeletal tissues. Vitamin D acts on target tissues via the binding of its active form to VDR. As vitamin D affects not only bone metabolism but also glucose metabolism, vitamin D deficiency may affect the development of gestational diabetes mellitus and fetal growth. Although vitamin D deficiency is prevalent during pregnancy, there are conflicting reports on the effect of vitamin D deficiency on pregnancy complications, such as fetal growth restriction and gestational diabetes. This article reviews published papers on the effects of vitamin D on gestational diabetes and fetal growth.
