The Result Of The Technological Research For Preparing Gel For Scald Disease From Mountain Butter
- Author:
Munkhzul P
1
;
Enkhjargal D
1
;
Jambaninj D
1
Author Information
1. School of Pharmacy.Health Sciences University of Mongolia
- Publication Type:Journal Article
- Keywords:
Mountain butter
- From:
Journal of Oriental Medicine
2012;3(2):67-69
- CountryMongolia
- Language:English
-
Abstract:
In the Traditional Medicine, traditional prescriptions and raw
materials of animal, plant and mineral origins have been widely
used in order to heal wounds, alleviate inflammation, kill
bacteria, and accelerate the development of blood cells.
These natural minerals or mountain butter /in the Russian
Traditional Medicine, named as каменное масло, in Western
Europe and the USA, named as Mountain Butter/ is the
aluminum-potassic alum /Telyaiev.V.V, 1985/ including
contamination of spunky saline originated in the mountain butter,
widely occurred in the mountain zones of the world. The alum or
mountain butter is widely overspread in Levitan, Leona, Alma in
California province of the USA, mountain region in Peris of
England, Plaka of Greece, Klara of Germany, Raphid Krik of
Canada, mountain region in Sebiria of Russian, areas near
Baikal lake, mountain regions in Khuvsgul and Bayan-Ulgii
provinces, and mountain region of Khamar Davaa along to the
boundary of Russia and Mongolia, consequently regional
residents have been using it as a solution for scald and burned
skin.
However, the scientists have been entitling the mountain butter
as tar of mineral origin, mountain butter and alum /A.Jusmin,
V.Chulanov/ etc during hundreds of years because it is
originated in rock chaps of mountain stony regions, other
substances impacted it, mixed with spoils and animal litters, as a
result of the spectrum analysis conducted in a chemical and
physical laboratory of the Scientific Institute under Sankt
Peterburg University of the Russian Federation, /Tabune E.V,
Mikhailov. V.V 1999/ it was certified that the mountain butter is
metallic pickering containing iron, magnesium, nickel, kali,
aluminum, foil and copper or alum (Fe, Mg) x A12 (SO4)4 x
22H20).
The scientist confirmed that the mountain butter or alum is the
matted yellowish and alkaline organic compound including a
variety of macro and micro elements and easily fades in water
and it has function to improve renewability of blood cells
/Shakirov A.,Uzbek, 1982/.
As a result of our analysis, the mountain butter has non-toxic
elements (As, Hg, Pb, Cd) for human body but there are a lot of
positive elements for human body and improves the digestion
and immunity. This is a pure natural product without any
negative impact and hindrance (A.Jusman, V.Chulanov,
Moskwa, 2009).
However, the scald disease of fire, household, chemical and
other origins are widely occurred among Mongolians, expensive
oil polishes /oitment, Vishnevskii, selimazin and argosulphone
etc/ are usually imported from foreign countries. In
Mongolianmedicine, the gel drugs of natural origin, made in
Mongolia, with active function for scald injuries, is rare,
consequently we conducted present research paper.
The preparation of gel from mountain butter
Objectives:
1. Select the appropriate gel bases from mountain butter 2. To
select pH neutralizer of gel spoiler condition and substance
improving absorbable quality 3. Preparation of gel and
determine the indicator of gel quality
Results: In accordance with the requirement for determining the
adequate correlation of substances to increase the infiltrating
quality in pH adapting dermis of gel originating and stabilizing
condition, the research paper was conducted by following way,
in order to prepare gel from mountain butter.
1. For the purpose to select the gel originator substance, the
clinging quality of the base containing 2% of carbomere was
convenient as a result of analysis the bases by absorbing the
5% and 10% of carboxymethyl celluse and
1%,1.2%,1.4%,1.6%,1.8%, 2%, 2.2%, 2.4% of carbometer
powder, and medical substance was completely absorbed and
originated equable mass, consequently it’s determined to select
5% of carboxymethyl celluse and 2% of carbomere as the gel
originator substance.
2. Although, carbomere originates acid reaction in water, base
Ph was 2,56 or excessive acidity, thus the crystal unsmooth
liquid mass was originated when blending it with main
substance, consequently the research to select the adequate
doze by choosing trietanolamin as the pH neutlalizer. In order to
select the adequate doze of trietanlamin, trietanlamin was
increased 0.5 gram to 0.25gram and 3 gram on the carbomere’s
base, and it’s determined that 3.0 trietanolamin is required to
disperify pH up to 5.75.
When studying the substance to improve quality humectants of
gel, 5%, 10% and 15% of glycerine was selected as the
substance increasing the hatching quality, and variation of the
mixing quality and gel’s spreading quality were studied in
comparison, and as a result of it, it’s more proper to 15% of
glycerine in order to improve the humectant quality of gel.
3. Conservant substances or 0.18 % of metilparaben and 0.02%
of propilparaben were prepared, admixed and absorbed in
distilled water previoursy heated, and added up carbomere and
disperified it. To coordinate the condition, neutralize it with 3% of
trietanolamin, the main reactor or 2% of mountain butter on 5-7
of pH was absorbed in distilled water, and added up it on base
and originated the smooth gel, in order to increase the
humectant quality, the quality requirement for gel pH, color,
liquidity, mixing quality, sort, and humectant quality were
provided.
Discussions: Based on the main positive aspects of the gel drug,
including on injured skin or surfaces of injuries effusive covering
was originated and effectively stick, not slimmed and tanned,
main medical substance is rapidly released, thin effusive
covering can completely separate from outer condition,
consequently we prepared the gel drug from mountain butter.
Researchers, M. Balkkhaev, D. Jambaninj prepared the gel
containing the galenical consistent infusion, and studied and
compared its quality with рН, humectant quality, and spreading
capability. In order to prepare the gel with galenical infusion,
carbomere (934) as gel originator substance, trietanolamin as
рН adapting substance, metilparaben and propilparaben as
conservant substance, glycerine as substance to increase the
hatching quality, were used separately and it рН was 7.02, and
spreading quality was 21.54. These explorers used the main and
accidental substances that are widely used to emulge the gel
drug, in their research by the modern methodology of medical
technology.
We prepared the water emulsion of the mountain butter and in
order to formulate the gel , 2% of carbomere as the originator
substance, 3% of trietanolamin as рН adapting substance,
0.18% of metilparaben and 0.02% of propilpparaben as
conservant substances, and 15% of glycerin as substance to
increase the humectant quality, were prepared separately and
obtained gel was agreeable with the result of other researchers’
paper and provided the criterions for standardization documents
and gel’s quality pharmacopoeia.
