Experimental Result Of “Sending-4” For Wound Healin G Activity Using Mice’s Incision Wound Models
- VernacularTitle:Цагаан Хулганад Үүсгэсэн Зүсэгдсэн Шархны Эмгэг Загварт Сэндэн4-Ийгтуршсан Дүн
- Author:
Soyolmaa Ts
1
;
Ariunaa Z
1
;
Oldokh S
1
;
Uuganbayar B
1
;
Dashtsermaa D
1
Author Information
1. Health Sciences University Of Mongolia
- Publication Type:Journal Article
- Keywords:
Acacia catechu, terminalia chebula, terminalia bel larice, gardenia jasminoides, ketamine
- From:
Journal of Oriental Medicine
2012;2(1):79-83
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background and Aim: The traditional herbal formulation of “Sendeng- 4”have been used to treat ulcers. The wound healing activity of traditional herbal formulations (Sendeng-4) containing Acacia catechu Willd (FamilyFabaceae), Terminalia chebula Retz, Terminalia bellarice (Family Combretaceae), Gardenia jasminoides (family Rubiaceae). We were prepared lotion of “Sendeng-4” was evaluated for its wound healing potential of incision wound models in mice’s. Material and Methods: Healthy inbred white mice’s were weighing 20-22 used for the study. The animals were randomly divided into two groups(n= 10) in all the models. The mice’swere anesthetized ketamine (12mg kg–1bodyweight) of the experimental wounds. We used comparable to that of lotion of thestandard drug and standard solution used for comparison in this present investigation. The results were also comparable of wound contracting ability, epithelization period, regeneration of tissues at the wound area. On Day 14-16th lotion of “Sendeng-4” treated animals exhibited 100% reductionin the wound area when compared to controls. The increased rate of woundcontraction, skin breaking strength and of “Sendeng-4” in wound healing. Conclution:The lotion of traditional herbal formulation of “Sendeng-4” have facilitateswound healing in the experimental animal model.
