The Study Of Some Parameters, Determined In A II Compartment Of The Modelling Of Rlung, Mkhris, Badgan Coded Situation By Inducing The Inhibition Of Mitochondrial Electron Transport Events In Experimental Animals
- VernacularTitle:Хий, Шар, Бадганы Кодчиллыг Туршлагын Амьтан Дээр Электрон, Протоныт Түвшинд Загварчлан Үүсгэсэн Үед1-Р Компартментийн Гемоглобины Исэлдүүлэх Чадамжид Шүдэн Цагаан Хунчирын Усан Хандны Үзүүлэх Нөлөөг Судалсан Дүн
- Author:
Narantsetseg J
1
;
Solongo Kh
1
;
Ambaga M
1
Author Information
1. Health Sciences University Of Mongolia
- Publication Type:Journal Article
- Keywords:
Rotenone;
dinitrofeny;
compartment;
membrane-redox;
potentiol
- From:
Journal of Oriental Medicine
2012;2(1):72-75
- CountryMongolia
- Language:Mongolian
-
Abstract:
The one of advantages, new events, appeared at lasttime in the integration part of Traditional and Modern medicine is attempt, proposed by prof. M.Ambaga, which essence is devoted to how to transform a all disordered knowledge accumulated in the field of medical science in a ordered more understandable form as new definition of living cells, the new conception of describing of human body by 4 compartments. The electron transport chain still functions to pump hydrogen ions into the intermembrane space, but the coupling of the proton gradient to ATP production is rendered impossible by DNP. As a result, ATP production is dramaticallyreduced, and the energy is instead thrown off as heat. DNP is lipophilic weak acids that therefore readily pass through membranes, they bind protons in the acidific side of the membrane-intermembrane spaces, diffuse through, and release them on the alkaline side-matrix side, thereby dissipating the proton gradient, metabolic rate is increased. Rotenone inhibits the oxidation of NADH to NAD, blocking the oxidation byNAD of substrates such as glutamate, alpha-ketoglutarate, and pyruvate. Rotenone inhibits the mitochondrial respiratory chain between diphosphopyridine nucleotide and flavine.
