The Chemical Analyses Of The Preparation Jonsh-6
- VernacularTitle:Жонш-6 Бэлдмэлийн Химийн Судалгааны Дүн
- Author:
Odgerel Ch
1
;
Daariimaa Kh
1
;
Soyolt T
1
;
Seesregdorj S
1
;
Davaasuren Ts
1
;
Chimedragchaa Ch
1
Author Information
1. Health Sciences University Of Mongolia
- Publication Type:Journal Article
- Keywords:
HPLC;
jonsh-6;
safflomin-A;
piperine;
alantolaktone and costunolide
- From:
Journal of Oriental Medicine
2012;2(1):21-27
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction Medicinal plants and herbal drug:Introduction Medicinal plants and herbal drugs have made and a tremendous contribution to national health and development from the very beginning. Fora very long time, people have used locally available medicinal plants for medicaltreatment and have eaten certain vegetables and spices for health protection as well as sustenance. Even though in traditional medicine, we use many different medicinal plants and herbal preparations for treatment of various diseases, most of them are not completely studied yet. One of these herbal preparations is Jonsh-6. The research group reported already that the preparation Jonsh-6 has pharmacological effects such as to treat diseases such as gastritis, stomach disorder (B.Uyanga, S.Seesregdorj, 2011) and at this time there aren’t any other studies made in respect to the preparation Jonsh-6. The aim of our research is to complete qualitical and quantitative analyses of biological active substance in the preparation Jonsh-6. Material and methods The contents of the preparation Jonsh-6 are Calcitum-0.3g, Piper longim L- 0.08g, Aucklanda lappa Decne-0,15g, Inula helenium L-0.15g, Carthamus tinctorius L-0.24g, Amomum Kravanh Pierreex Gagnep-0.08g.Analyses of the preparation were studied by using HPLC on Waters Delta 600 Pump, Waters 600 Controller, Waters 2487 DualχAbsorbance Detector, Pinnacle II C18 5μm, 250x4.6 ммand selected following conditions: mobile phase: Acetonitrile:water/50:50,Acetonitrile:0.7% phosphoric acid /25:75,wavelength 210, 338, 403 nm, Detector: UVvis, column: Pinnacle IIC18 5μm (250x4.6 мм), flow rate 1.0 ml/min. Key words: HPLC, Jonsh-6, Safflomin-A, Piperine, Alantolaktone, and Costunolide. Conclusion In order to succeed the above mentioned aim, we have achieved the following results:
3. The chromatographical method and methodology forthe qualitical and quantitative analyses of main compounds in the preparation Jonsh-6 were developed using HPLC.
4. The quantity of main components in the preparation Jonsh-6 were determined with HPLC and Safflomin-A 1.06 mg, piperine 0.195 mg, alantolaktone 1.12 mg and costunolide 0.925 mg are contained in 1.003 gm of the preparation.
