Results Of Study On Traditional Drug Sendeng 4 For Papain-Induced Osteoarthritis In Rats
- VernacularTitle:Харханд Папайнаар Үүсгэсэн Үений Үрэвслийн Эмгэг Загварт Уламжлалт Эм “Сэндэн 4”-Ийн Нөлөөг Судалсан Дүн
- Author:
Ariunaa Z
1
;
Oldokh S
1
;
Soyolmaa Ts
1
;
Uuganbayar
1
;
Dashtsermaa D
1
;
Khongorzul D
1
Author Information
1. Traditional Medical Science, Technology and Production Corporation
- Publication Type:Journal Article
- Keywords:
Senden 4;
indomon;
patophysiological design of arthritis;
papain;
cystein
- From:
Journal of Oriental Medicine
2011;1(1):55-58
- CountryMongolia
- Language:Mongolian
-
Abstract:
Objectives: To study of the effects on traditional drug Sendeng 4 for papain-induced osteoarthritis in rats. Methods: The rats were divided into three equal groups in number and were sacrificed under high-dose ether anesthesia after one, two, and four weeks of the last papain injection, respectively. Osteoarthritis was experimented in Wistar rats. Total 21 rats were injecting an admixture of 4% papain and its activator 0.03 M cycteine into the right knee joints on the first, fourth, and seventh days. The same volume of sterile saline solution was injected into the left knees as controls. Result. Pre sacrifice, measured with the artritis scoring evalution and X ray analysis, after cartilage from femorel condyles and tibial plateaus was macroscopically and histophatologically evaluated. The artritis scoring evalution were significantly lower at Sendeng 4 groups (2.2±0.16) compared to the control (3.7±0.25) groups. (p
