Prospective Multicenter Observational Study on Postoperative Quality of Life According to Type of Gastrectomy for Gastric Cancer
- Author:
Sung Eun OH
1
;
Yun-Suhk SUH
;
Ji Yeong AN
;
Keun Won RYU
;
In CHO
;
Sung Geun KIM
;
Ji-Ho PARK
;
Hoon HUR
;
Hyung-Ho KIM
;
Sang-Hoon AHN
;
Sun-Hwi HWANG
;
Hong Man YOON
;
Ki Bum PARK
;
Hyoung-Il KIM
;
In Gyu KWON
;
Han-Kwang YANG
;
Byoung-Jo SUH
;
Sang-Ho JEONG
;
Tae-Han KIM
;
Oh Kyoung KWON
;
Hye Seong AHN
;
Ji Yeon PARK
;
Ki Young YOON
;
Myoung Won SON
;
Seong-Ho KONG
;
Young-Gil SON
;
Geum Jong SONG
;
Jong Hyuk YUN
;
Jung-Min BAE
;
Do Joong PARK
;
Sol LEE
;
Jun-Young YANG
;
Kyung Won SEO
;
You-Jin JANG
;
So Hyun KANG
;
Bang Wool EOM
;
Joongyub LEE
;
Hyuk-Joon LEE
;
Author Information
- Publication Type:Original Article
- From:Journal of Gastric Cancer 2025;25(2):382-399
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:This study evaluated the postoperative quality of life (QoL) after various types of gastrectomy for gastric cancer.
Materials and Methods:A multicenter prospective observational study was conducted in Korea using the Korean Quality of Life in Stomach Cancer Patients Study (KOQUSS)-40, a new QoL assessment tool focusing on postgastrectomy syndrome. Overall, 496 patients with gastric cancer were enrolled, and QoL was assessed at 5 time points: preoperatively and at 1, 3, 6, and 12 months after surgery.
Results:Distal gastrectomy (DG) and pylorus-preserving gastrectomy (PPG) showed significantly better outcomes than total gastrectomy (TG) and proximal gastrectomy (PG) with regard to total score, indigestion, and dysphagia. DG, PPG, and TG also showed significantly better outcomes than PG in terms of dumping syndrome and worry about cancer. Postoperative QoL did not differ significantly according to anastomosis type in DG, except for Billroth I anastomosis, which achieved better bowel habit change scores than the others. No domains differed significantly when comparing double tract reconstruction and esophagogastrostomy after PG. The total QoL score correlated significantly with postoperative body weight loss (more than 10%) and extent of resection (P<0.05 for both).Reflux as assessed by KOQUSS-40 did not correlate significantly with reflux observed on gastroscopy 1 year postoperatively (P=0.064).
Conclusions:Our prospective observation using KOQUSS-40 revealed that DG and PPG lead to better QoL than TG and PG. Further study is needed to compare postoperative QoL according to anastomosis type in DG and PG.
