T2 Values of Femoral Cartilage of the Knee Joint: Comparison between Pre-Contrast and Post-Contrast Images.
10.3348/kjr.2014.15.1.123
- Author:
Hyun Jung YOON
1
;
Young Cheol YOON
;
Bong Keun CHOE
Author Information
1. Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea. youngcheol.yoon@gmail.com
- Publication Type:Original Article
- Keywords:
Magnetic resonance;
Cartilage, articular;
Osteoarthritis;
T2 mapping;
dGEMRIC
- MeSH:
Adult;
Aged;
*Cartilage, Articular/pathology;
Contrast Media/*diagnostic use;
Female;
Femur;
Gadolinium DTPA/diagnostic use;
Humans;
Knee Joint;
Magnetic Resonance Imaging/*methods;
Male;
Middle Aged;
Osteoarthritis, Knee/*diagnosis/pathology;
Retrospective Studies
- From:Korean Journal of Radiology
2014;15(1):123-129
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To retrospectively evaluate the relationship between T2 values of pre- and post-contrast magnetic resonance (MR) images of femoral cartilage in patients with varying degrees of osteoarthritis. MATERIALS AND METHODS: A total of 19 patients underwent delayed gadolinium-enhanced MRI of cartilage. Six regions of interest for T2 value measurement were obtained from pre- and post-contrast T2-weighted, sagittal, multi-slice, multi-echo, source images in each subject. Regions with modified Noyes classification grade 2B and 3 were excluded. Comparison of T2 values between pre- and post-contrast images and T2 values among regions with the grade 0, 1 and 2A groups were statistically analyzed. RESULTS: Of a total of 114 regions, 79 regions showing grade 0 (n = 46), 1 (n = 18), or 2A (n = 15) were analyzed. The overall and individual T2 values of post-contrast images were significantly lower than those of pre-contrast images (overall, 35.3 +/- 9.2 [mean +/- SD] vs. 29.9 +/- 8.2, p < 0.01; range of individual, 28.9-37.6 vs. 27.1-36.4, p < 0.01). Pearson correlation coefficients showed a strong positive correlation between pre- and post-contrast images (rho-Pearson = 0.712-0.905). T2 values of pre- and post-contrast images of the grade 0 group were significantly lower than those of the grade 1/2A group (pre T2, p = 0.003; post T2, p = 0.006). CONCLUSION: T2 values of the femoral cartilage of the knee joint are significantly lower on post-contrast images than on pre-contrast images. Furthermore, these T2 values have a strong positive correlation between pre- and post-contrast images.
