Effect of UV - B Radiation on Epidermal Melanocytes of C 57BL Mouse.
- Author:
Young Keun KIM
;
Yoon Kee PARK
;
Hong Jig KIM
- Publication Type:Original Article
- Keywords:
Melanocyte;
UVB;
Electron microscopy
- MeSH:
Animals;
Dihydroxyphenylalanine;
Melanocytes*;
Mice*;
Microscopy, Electron;
Mitosis
- From:Korean Journal of Dermatology
1988;26(2):139-144
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was undertaken to investigate the effect of UVB radiation on epidermal melanoctes of C57BIL mouse, The results are summarized as follows : l) The numerical increase of DOPA positive melanocytes following UVB irradiation was due to both of active mitosis of epidermal melanocytes and the conversion of dormant. malanocytes to DOPA-positive melsnocytes. 2) Long term effects of UVB irradiatinn on the epidermal melanocytes suggest the persistent activation of typrosinase in UVB irradiated melanocytes.