JR Blood Group and Anti-Jra Antibody
10.17945/kjbt.2024.35.3.1 6 7
- Author:
Soon Sung KWON
1
;
Sinyoung KIM
Author Information
1. Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea
- Publication Type:Review Article
- From:Korean Journal of Blood Transfusion
2024;35(3):167-177
- CountryRepublic of Korea
- Language:English
-
Abstract:
The Jr(a+) antigen is one of the high-frequency antigens belonging to the JR blood group system. Although the clinical significance of anti-Jra is not well defined, cases of hemolytic disease of the newborn and hemolytic transfusion reactions caused by anti-Jra have been reported. This review introduces the genetic background of the JR blood group, the frequency of Jr(a+), and the clinical significance of anti-Jra based on existing literature.Additionally, it summarizes the identification of anti-Jra and the transfusion strategies that can be adopted for patients with anti-Jra alloantibodies.