Measurement of Vaginal Blood Flow using Laser Doppler Flowmetry in Rabbit.
- Author:
Sun Ouck KIM
1
;
Myeong Jeong CHAE
;
Hyun Suk LEE
;
Jae Dong MOON
;
Kwangsung PARK
Author Information
1. Department of Urology, Chonnam National University Medical School, Gwangju, Korea. kpark@jnu.ac.kr
- Publication Type:Original Article
- Keywords:
Blood flow;
Vagina;
Rabbit;
Laser Doppler flowmeter
- MeSH:
Female;
Humans;
Laser-Doppler Flowmetry*;
New Zealand;
Vagina
- From:Korean Journal of Andrology
2005;23(2):100-103
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: One of the problems using laser doppler flowmetry is variability in the measurements. The purposes of this study were to investigate the regional differences of vaginal blood flow using laser Doppler flowmetry and to suggest a method to enhance the accuracy of measurement. MATERIALS AND METHODS: In New Zealand White female rabbits(3.0~3.5 kg, n=10), vaginal blood flow was measured by laser doppler flowmetry using a surface probe. Flow was measured at the anterior, posterior, left, and right side of vaginal wall in each vaginal introitus and proximal 2 cm of the vaginal wall. Each site was measured 3 times separately. The data were analyzed using two-way ANOVA and repeated measures ANOVA. RESULTS: Regional vaginal blood flows(ml/min/100 gm tissue) at the anterior, posterior, left, and right vaginal wall were 19.7+/-8.7, 19.6+/-7.3, 19.3+/-7.8, 18.8+/-7.2 at vaginal introitus and 27.3+/-8.8, 18.9+/-7.5, 22.6+/-7.1, 20.8+/-5.7 at the proximal 2 cm of vaginal introitus, respectively. Differences were not statistically significant(p> 0.05), as there was a wide range of variation. CONCLUSIONS: Vaginal blood flow did not show any regional differences in the distal part of the rabbit vagina. Repeated measurements may decrease the variation of vaginal blood flow by laser Doppler flowmetry.
