Characteristics and outcomes of portal vein thrombosis in patients with inflammatory bowel disease in Korea
- Author:
Ki Jin KIM
1
;
Su-Bin SONG
;
Jung-Bin PARK
;
June Hwa BAE
;
Ji Eun BAEK
;
Ga Hee KIM
;
Min-Jun KIM
;
Seung Wook HONG
;
Sung Wook HWANG
;
Dong-Hoon YANG
;
Byong Duk YE
;
Jeong-Sik BYEON
;
Seung-Jae MYUNG
;
Suk-Kyun YANG
;
Chang Sik YU
;
Yong-Sik YOON
;
Jong-Lyul LEE
;
Min Hyun KIM
;
Ho-Su LEE
;
Sang Hyoung PARK
Author Information
- Publication Type:2
- From:The Korean Journal of Internal Medicine 2025;40(2):243-250
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background/Aims:Portal vein thrombosis (PVT) frequently occurs in patients with inflammatory bowel disease (IBD), particularly when influenced by factors such as abdominal infections, IBD flare-ups, or surgical procedures. The implications of PVT range from immediate issues such as intestinal ischemia to long-term concerns including portal hypertension and its complications. However, there is a notable gap in comprehensive studies on PVT in IBD, especially with the increasing incidence of IBD in Asia. This research aimed to evaluate the clinical features and outcomes of PVT in patients with IBD at a leading hospital in South Korea.
Methods:This retrospective analysis reviewed adult patients diagnosed with both IBD and PVT from 1989 to 2021 at a renowned South Korean medical center. The study focused on patient characteristics, specifics of PVT, administered treatments, and outcomes, all confirmed through enhanced CT scans.
Results:A total of 78 patients met the study’s criteria. Notably, only 20.5% (16/78) were treated with oral anticoagulants; however, a vast majority (96.2%; 75/78) achieved complete radiographic resolution (CRR). When comparing patients receiving anticoagulants to those who did not, a significant preference for anticoagulant use was observed in cases where the main portal vein was affected, as opposed to just the left or right veins (p = 0.006). However, multivariable analysis indicated that neither anticoagulant use nor previous surgeries significantly impacted CRR.
Conclusions:Patients with IBD and PVT generally had favorable outcomes, regardless of anticoagulant use.
