High-resolution MR Imaging of Carotid Atherosclerotic Plaques.
10.13104/jksmrm.2012.16.2.97
- Author:
Wonseon SHIN
1
;
Sung Mok KIM
;
Yeon Hyeon CHOE
Author Information
1. Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yhchoe@skku.edu
- Publication Type:Review
- Keywords:
Atheroslcerosis;
Carotid artery;
Magnetic resonance imaging (MRI)
- MeSH:
Carotid Arteries;
Dextrans;
Hemorrhage;
Inflammation;
Iron;
Ischemic Attack, Transient;
Magnetite Nanoparticles;
Plaque, Atherosclerotic;
Signal-To-Noise Ratio;
Stroke
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2012;16(2):97-102
- CountryRepublic of Korea
- Language:English
-
Abstract:
High-resolution carotid MRI allows visualization of carotid atherosclerotic plaque characteristics. MRI serves as a noninvasive option for the detection of active plaque inflammation and intraplaque hemorrhage. Significant gains in signal-to-noise ratio and contrast-to-noise ratio can be obtained for carotid atheroma imaging at 3T compared with 1.5T. Normalized wall index or wall area on MRI has shown its efficacy in monitoring the response after medical therapy. T(2)* quantification in carotid plaques before and after the administration of ultrasmall superparamagnetic iron oxide particles shows difference in response to treatment according to drug doses. In conclusion, high-resolution MRI is useful in the diagnosis and monitoring of carotid atherosclerotic plaques prone to transient ischemic attack and stroke.
