Multiple Cranial Neuropathies Without Limb Involvements: Guillain-Barre Syndrome Variant?.
10.5535/arm.2013.37.5.740
- Author:
Ju Young YU
1
;
Han Young JUNG
;
Chang Hwan KIM
;
Hyo Sang KIM
;
Myeong Ok KIM
Author Information
1. Department of Physical and Rehabilitation Medicine, Inha University School of Medicine, Incheon, Korea. rmkmo@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Guillain-Barre syndrome;
Cranial neuropathies;
Bulbar palsy
- MeSH:
Ataxia;
Bulbar Palsy, Progressive;
Communicable Diseases;
Cranial Nerve Diseases*;
Cranial Nerves;
Extremities*;
Facial Nerve;
Guillain-Barre Syndrome*;
Humans;
Immunoglobulin G;
Male;
Middle Aged;
Paralysis;
Rare Diseases;
Walking
- From:Annals of Rehabilitation Medicine
2013;37(5):740-744
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acute multiple cranial neuropathies are considered as variant of Guillain-Barre syndrome, which are immune-mediated diseases triggered by various cases. It is a rare disease which is related to infectious, inflammatory or systemic diseases. According to previous case reports, those affected can exhibit almost bilateral facial nerve palsy, then followed by bulbar dysfunctions (cranial nerves IX and X) accompanied by limb weakness and walking difficulties due to motor and/or sensory dysfunctions. Furthermore, reported cases of the acute multiple cranial neuropathies show electrophysiological abnormalities compatible with the typical Guillain-Barre syndromes (GBS). We recently experienced a patient with a benign infectious disease who subsequently developed symptoms of variant GBS. Here, we describe the case of a 48-year-old male patient who developed multiple symptoms of cranial neuropathy without limb weakness. His laboratory findings showed a positive result for anti-GQ1b IgG antibody. As compared with previously described variants of GBS, the patient exhibited widespread cranial neuropathy, which included neuropathies of cranial nerves III-XII, without limb involvement or ataxia.
