A Case of Middle Mediastinal Malignant Paraganglioma.
10.4046/trd.2011.70.2.165
- Author:
Sung Bum PARK
1
;
Silvia PARK
;
Sun Ha BANG
;
Eun Kyung KIM
;
Kyeongman JEON
;
Won Jung KOH
;
Gee Young SUH
;
Man Pyo CHUNG
;
Hojoong KIM
;
O Jung KWON
;
Young Hyeh GO
;
Sang Won UM
Author Information
1. Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Paraganglioma;
Mediastinum;
Neoplasms
- MeSH:
Adrenal Medulla;
Chromaffin Cells;
Headache;
Humans;
Mediastinoscopy;
Mediastinum;
Neuroendocrine Tumors;
Paraganglioma;
Pheochromocytoma;
Thorax;
Voice
- From:Tuberculosis and Respiratory Diseases
2011;70(2):165-169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas. However, cases of middle mediastinal paragangliomas are very rare. In this case, the patient presented with a voice change and a headache. A middle mediastinal soft tissue mass with marked enhancement was detected on computed tomography of the chest. The 24-hour urine catecholamine level was markedly elevated. The middle mediastinal mass was biopsied via mediastinoscopy and the resulting immunohistochemical staining was compatible with a diagnosis of middle mediastinal paraganglioma. The mass was resected surgically and the symptoms were relieved.
