Paget's Disease of the Male Breast.
10.5021/ad.1992.4.1.32
- Author:
Yong Myo PARK
;
Jong Cheul KIM
;
Jong Soo CHOI
;
Ki Hong KIM
- Publication Type:Case Report
- Keywords:
Male breast;
Paget's disease of the breast
- MeSH:
Adenocarcinoma;
Breast*;
Carcinoembryonic Antigen;
Drug Therapy;
Female;
Humans;
Juglans;
Lymph Nodes;
Male*;
Mastectomy, Modified Radical;
Middle Aged;
Neoplasm Metastasis;
Nipples;
Paget's Disease, Mammary;
S100 Proteins;
Skin
- From:Annals of Dermatology
1992;4(1):32-36
- CountryRepublic of Korea
- Language:English
-
Abstract:
Paget's disease of the breast occurs almost exclusively in women, and is characterized by a unilateral, sharply defined eczematous skin lesion caused by epidermal metastases from underlying ductal adenocarcinoma of the breast. Paget's disease of the male breast is extremely rare. A 61-year-old patient had a skin lesion on the right nipple for 1 year. The lesion was a well defined, brownish, crusted, and keratotic papule, and was associated with an underlying walnut sized, fixed, hard mass and a palpable ipsilateral axillary lymph node. Histologic findings were consistent with Paget's disease. Results of immunoperoxidase staining technigues for S-100 protein and carcinoembryonic antigen were negative. After a modified radical mastectomy and chemotherapy, the patient has been in remission for 12 months.
