A Comparison Study of Two Different Methods of Administration: Intranasal versus Intramuscular for Pediatric Procedural Sedation and Analgesia.
- Author:
Kyoung Chan AN
1
;
Jung Hwan AHN
;
Kug Jong LEE
;
Yoon Seok JUNG
;
Sang Cheon CHOI
;
Young Shin CHO
;
Ji Sook LEE
;
Choung Ah LEE
;
Gi Woon KIM
Author Information
1. Department of Emergency Medicine, Ajou University School of Medicine, Korea. flyingguy@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Intranasal Administration;
Intramuscular Injection;
Ketamine;
Conscious Sedation
- MeSH:
Administration, Intranasal;
Analgesia;
Child;
Conscious Sedation;
Emergencies;
Humans;
Injections, Intramuscular;
Ketamine;
Lacerations;
Parents;
Prospective Studies
- From:Journal of the Korean Society of Emergency Medicine
2009;20(4):422-427
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To compare the efficacy of ketamine between intranasal (IN) administration and intramuscular (IM) injection for pediatric procedural sedation and analgesia (PPSA). METHODS: A prospective study was conducted during 3 months. Ketamine was given by IN or IM route before primary repair of facial laceration for procedural sedation. The administration dose was 8 mg/kg for IN and 4 mg/kg for IM. We evaluated resistance scale on administration, sedation scale, satisfaction of physician and parents. RESULTS: One hundred children were enrolled into this study. IN administration was given to 50 children, and IM injection to 50 children each. In the IN group, 75%(36 of 50) showed severe resistance, whereas only 34%(17 of 50) showed severe resistance and 50%(25 of 50) showed mild resistance in IM group. Successful rate of sedation after initial administration was 82%(41 of 50) in IM group and 34% in IN group. Satisfaction of physicians and parents was high in IM injection group. CONCLUSION: Intranasal administration of Ketamine is less effective and provides lower satisfaction than intramuscular injection for procedural sedation of pediatric patients in the emergency department.
