The distribution of lymphocytic subsets in bone marrow of acute leukemia patients -subtypes M1,M 2, M3
- Author:
Toan Huu Nguyen
- Publication Type:Journal Article
- Keywords:
leukemia
- MeSH:
Leukemia;
bone marrow
- From:Journal of Vietnamese Medicine
2001;267(12):36-41
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The results showed that, the cell counts are widely diffrerent among patients and subtypes. In M2 subtype, lymphocyte T and NK cell counts refered to elevate in peripheral blood and more clearly in bone marrow but CD4/8 ratio remains so normal. M1 subtype displayed the disorder and partial insuffiency of cellular number and distribution. B cell count is dicreased markedly both in peripheral blood and bone marrow and NK cell count is dicreased only in bone marrow. In M3 subtype, all of subtypes are depletted in peripheral blood with immunologic disbalance. While it is not decreaed clearly in bone marrow, even lymphocyte TCD8 has tendency to a little evaluation inducing to CD4/8 ratio decreased. Comparison of 3 subtypes in cellular number and distribution showed that, M2 subtype has immunological capacity better than the remainders. this seem to be stable. NK cell and lymphocyte TCD8 counts are relatively high in M2 subtype; while NK cell is decreased in M1 and more clearly in M3 subtype
