Transfusion Strategy and Laboratory Update on the DEL Variant.
10.17945/kjbt.2015.26.1.1
- Author:
Min Hee SEO
1
;
Borahm KIM
;
Jeong Ran KWON
;
Young Sill CHOI
;
Jun Nyun KIM
;
Kyoung Un PARK
;
Duck CHO
Author Information
1. Department of Biomedical Sciences, Chonnam National University, Gwangju, Korea.
- Publication Type:Review
- Keywords:
RHD;
DEL;
Transfusion;
Genotyping
- MeSH:
Adsorption;
Blood Donors;
Erythrocytes;
Humans;
Serologic Tests
- From:Korean Journal of Blood Transfusion
2015;26(1):1-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Red cells that express extremely low levels of D antigen that cannot be detected by routine serologic tests are designated as DEL. Most DEL blood donors are typed as D-negative. However, DEL red blood cells can be recognized by serological adsorption and elution test or molecular RHD genotyping. Anti-D production in patients with D-negative who received transfusion containing DEL blood has reported, therefore distinction between DEL variant and true D- negative is clinically important. This review highlights a transfusion strategy and laboratory update on the DEL variant in the Korean population.
