Nipple swab culture profile as a potential predictor of postoperative complications in autologous breast reconstruction: a retrospective study
- Author:
Sun-Hyeok KIM
1
;
Yi-Jun MOON
;
Seung-Pil JUNG
;
Hyung-Chul LEE
;
Jae-Ho CHUNG
;
Eul-Sik YOON
Author Information
- Publication Type:Original Article
- From:Archives of Aesthetic Plastic Surgery 2025;31(2):35-40
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:The nipple is a potential source of pathogens because its lactiferous ducts act as direct conduits from the nipple–areolar complex to the breast parenchyma. Our previous studies identified breast microbiota as a factor in postoperative complications following immediate breast reconstruction using silicone implants and acellular dermal matrix. This study aimed to investigate the correlation between preoperative nipple swab microbiota and the incidence of surgical site infections (SSIs) after autologous breast reconstruction.
Methods:We conducted a retrospective chart review of patients who underwent autologous breast reconstruction following total mastectomy. Preoperative nipple swab cultures were obtained. Patient demographics, surgical characteristics, and complication rates were compared between culture-positive and culture-negative groups. Microbiological data, including antibiotic‑resistance profiles, were collected.
Results:Among 39 reconstructed breasts, 18 (46.9%) had positive preoperative nipple cultures. The mean duration of drain placement was significantly longer in the culture‑positive group (14.39±3.96 days) than in the culture‑negative group (12.14±2.76 days, P=0.045). Methicillin‑susceptible Staphylococcus epidermidis accounted for 55.0% of isolates. Of the four SSIs observed, three occurred in patients with positive preoperative cultures.
Conclusions:Although pathogen strains differed between preoperative and postoperative settings, obtaining preoperative nipple microflora cultures and determining antibiotic‑resistance profiles can guide immediate antibiotic selection for SSIs and enhance postoperative management.
