A rare case of a large solid pseudopapillary neoplasm with extensive liver metastasis
- Author:
Jun Hyung KIM
1
;
Hyung Sun KIM
;
Jung Min LEE
;
Ji Hae NAHM
;
Joon Seong PARK
Author Information
- Publication Type:Case Report
- From: Annals of Hepato-Biliary-Pancreatic Surgery 2025;29(1):83-87
- CountryRepublic of Korea
- Language:English
- Abstract: Solid pseudopapillary neoplasms (SPNs) are uncommon pancreatic tumors that primarily affect young females. We report a case of a 24-year-old female diagnosed with SPN and liver metastasis during a routine examination. Imaging revealed an 8-cm pancreatic mass with multiple liver metastases. Histopathology confirmed SPN. Subsequent next-generation sequencing revealed a CTNNB1 mutation.The patient underwent a total pancreatectomy with splenectomy, right hemihepatectomy, and intraoperative radiofrequency ablation.Two years after the surgery, she remained complication-free. She is under regular surveillance. This case underscores the importance of early detection and comprehensive management of SPN.
