Values of surface membrane markers of blast in acute leukemia classification
- Author:
Toan Huu Nguyen
- Publication Type:Journal Article
- Keywords:
leukemia
- MeSH:
Leukemia;
diagnosis
- From:Journal of Vietnamese Medicine
1999;233(2):25-31
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
We carried out the classification of acute leukemia of 210 adult patients hospitalization at NIHBT during years of 1996-97 by two method of morphocytochemistry and immuno-phenotyping.The purposes are to evaluate the limitations of morphocytochemical method and values of immunophenotyping method to take a part to applicate well this superior method to pathologic study and treatment of acute leukemia in Vietnam. The results showed that there are some special types such as biphenotypic acute leukemia,, null cell AL, stem cell AL and NKAL. 55 out of 210 patients have to correct the result of morpho-cytochemistry by immunophenotyping. Even in common morphological subtypes, it is seen also some mistakes of classfication by the limitation of this method. Immunophenotyping method will define well on M0 subtype, really cellular lineage of ALL, mixed AL, stem cell AL and NK AL.These subtype could not be defined by morphocytochemical method
