Primary Cutaneous Cryptococcosis Treated with Fluconazole.
- Author:
Hee Young KANG
1
;
Nam Soo KIM
;
Eun So LEE
Author Information
1. Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
- Publication Type:Case Report
- Keywords:
Primary cutaneous cryptococcosis;
Fluconazole
- MeSH:
Cryptococcosis*;
Cryptococcus neoformans;
Cycloheximide;
Debridement;
Dermis;
Female;
Fluconazole*;
Forearm;
Humans;
Middle Aged;
Saccharomycetales;
Spores;
Ulcer
- From:Korean Journal of Dermatology
2000;38(6):838-840
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of primary cutaneous cryptococcosis in a 63-year-old female, who had a painful deep ulceration on the left forearm for 2 months. Histopathological examination showed numerous encapsulated round spores in the dermis and subcutis. A tissue culture on Sabouraud's media without cycloheximide showed whitish creamy colonies and revealed budding yeast cells in lactophenol cotton blue preparations. The organism was identified as Cryptococcus neoformans. The lesion was successfully treated with oral fluconazole(400 mg/day) for 2 months combined with surgical debridement.
