A Case of Solitary Circumscribed Neuroma.
10.5021/ad.2000.12.1.44
- Author:
Ji Young LEE
;
Chun Wook PARK
;
Cheol Heon LEE
- Publication Type:Case Report
- Keywords:
Solitary circumscribed neuroma
- MeSH:
Actins;
Biopsy;
Female;
Fingers;
Humans;
Joints;
Middle Aged;
Mitosis;
Mucin-1;
Muscle, Smooth;
Neuroma*;
Phosphopyruvate Hydratase;
S100 Proteins;
Vimentin
- From:Annals of Dermatology
2000;12(1):44-47
- CountryRepublic of Korea
- Language:English
-
Abstract:
Solitary circumscribed neuroma is a benign nerve sheath tumor of unknown etiology. Clinically, it appears as a long-standing, solitary, asymptomatic, skin-colored papule or papulonodule. It has been found predominantly on the face in both sexes, mostly in middle age. A 53-year-old female patient visited our department because of a nodule on the side of the distal interphalangeal joint of the left second finger. A biopsy specimen showed a well-circumscribed, partially encapsulated tumor composed of interlacing fascicles of spindle cells. Neither pleomorphism nor mitosis was found. Immunohistochemical stainings for vimentin, neuron specific enolase (NSE) and epithelial membrane antigen (EMA) were positive, but negative for S-100 protein and smooth muscle actin (SMA). We herein report an uncommon case of solitary circumscribed neuroma.
