Anaphylaxis with angioedema by rocuronium during induction of general anesthesia: A case report.
10.4097/kjae.2010.58.4.391
- Author:
Won Ju JEONG
1
;
Woon Young KIM
;
Joo Hyung SON
;
Yoon Sook LEE
;
Jae Hwan KIM
;
Young Cheol PARK
Author Information
1. Department of Anesthesiology and Pain Medicine, Korea University College of Medicine, Ansan Hospital, Ansan, Korea. ckssis@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Anaphylaxis;
Angioedema;
Intradermal skin test;
Rocuronium
- MeSH:
Adult;
Anaphylaxis;
Androstanols;
Anesthesia, General;
Angioedema;
Ephedrine;
Exanthema;
Eyelids;
Female;
Humans;
Hydrocortisone;
Hypersensitivity;
Hypotension;
Laser Therapy;
Propofol;
Skin;
Skin Tests;
Tachycardia;
Urticaria;
Varicose Veins;
Vital Signs
- From:Korean Journal of Anesthesiology
2010;58(4):391-395
- CountryRepublic of Korea
- Language:English
-
Abstract:
Perioperative anaphylaxis is characterized by severe respiratory and cardiovascular manifestations. Correct management of anaphylaxis during anaesthesia requires a multidisciplinary approach with prompt recognition and treatment of the acute event by the attending anesthesiologist. A 34-year-old woman was scheduled to undergo endo venous laser therapy of varicose veins. She had no history of allergies and had never undergone general anesthesia. General anesthesia was induced with propofol and rocuronium bromide. Approximately three minutes after rocuronium administration, hypotension and tachycardia developed and angioedema around the eyelids and skin rashes and urticaria appeared. The patient received ephedrine and hydrocortisone with hydration. After achieving stable vital signs and symptom relief, surgery was performed without complications. A postoperative skin dermal test performed to identify the agent responsible revealed a positive skin test for rocuronium.
