Kimura Disease Recurred in the Right Parotid Gland: A Case Report
10.21593/kjhno/2025.41.1.13
- Author:
Juyoung KIM
1
;
Young Kyun HUR
;
Kyung Hwan KIM
;
Nam Suk SIM
Author Information
1. Department of Otorhinolaryngology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
- Publication Type:Case Report
- From:
Korean Journal of Head and Neck Oncology
2025;41(1):13-16
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kimura’s disease is a rare, chronic inflammatory disorder that typically presents as painless head and neck masses in young Asian males, often accompanied by peripheral eosinophilia and elevated IgE levels. We report a case of recurrent Kimura’s disease involving the right parotid gland in a 35-year-old man, previously treated surgically. Due to tumor size (6 cm) and high risk of surgical complications, the patient underwent radiotherapy (30 Gy/15 fractions). Post-treatment imaging showed significant tumor reduction with no adverse effects or recurrence during 12 months of follow-up. While surgery remains the mainstay of treatment, recent studies suggest that radiotherapy or immunosuppressive therapy may be effective, especially in cases at high risk of recurrence. A recent meta-analysis identified tumor size ≥3 cm, prolonged disease duration (5 years), high eosinophil percentage (20%), and elevated IgE (10,000 IU/ml) as significant recurrence predictors. This case supports that radiotherapy may sere as a valuable treatment option when surgery in contraindicated or in high-risk recurrent cases.
