Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results
- Author:
Jong-Il PARK
1
;
Young-Guk KO
;
Seung-Jun LEE
;
Chul-Min AHN
;
Seung-Woon RHA
;
Cheol-Woong YU
;
Jong Kwan PARK
;
Sang-Ho PARK
;
Jae-Hwan LEE
;
Su-Hong KIM
;
Yong-Joon LEE
;
Sung-Jin HONG
;
Jung-Sun KIM
;
Byeong-Keuk KIM
;
Myeong-Ki HONG
;
Donghoon CHOI
Author Information
- Publication Type:Original Research
- From:Korean Circulation Journal 2024;54(8):454-465
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background and Objectives:The popliteal artery is generally regarded as a “no-stent zone.”Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease.
Methods:This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular therapy using IN.PACT DCB (Medtronic) for symptomatic atherosclerotic popliteal artery disease. The primary endpoint was 12-month clinical primary patency and the secondary endpoint was clinically driven target lesion revascularization (TLR)–free rate.
Results:The mean age of the study cohort was 65.7±10.8 years, and 77% of enrolled patients were men. The mean lesion length was 93.7±53.7 mm, and total occlusions were present in 45% of patients. Technical success was achieved in all patients. Combined atherectomy was performed in 17% and provisional stenting was required in 11%. Out of the enrolled patients, 91 patients completed the 12-month follow-up. Clinical primary patency and TLR-free survival rates at 12 months were 76.0% and 87.2%, respectively. A multivariate Cox regression analysis identified female and longer lesion length as the significant independent predictors of loss of patency.
Conclusions:DCB treatment yielded favorable 12-month clinical primary patency and TLRfree survival outcomes in patients with popliteal artery disease.
