Unraveling distinctions between contrast-enhanced ultrasound and CT/MRI for liver mass diagnosis

Author: Vanessa MURAD ¹ ; Hyun-Jung JANG ; Tae Kyoung KIM
Author Information

1. University Medical Imaging Toronto, Joint Department of Medical Imaging - University Health Network, Sinai Health System, Women’s College Hospital, University of Toronto, Toronto, Canada
Publication Type:2
From: Ultrasonography 2025;44(1):19-30
CountryRepublic of Korea
Language:English
Abstract: Contrast-enhanced ultrasound (CEUS) offers a distinctive approach to liver mass diagnosis by utilizing intravenous contrast agents for enhanced visualization of vascular structures and tissue characterization. This review highlights the unique advantages of CEUS compared to computed tomography (CT) and magnetic resonance imaging (MRI), particularly focusing on the Liver Imaging Reporting and Data System framework. Key differences include CEUS’s realtime imaging capability, which minimizes arterial phase mistiming and improves detection of hyperenhancing lesions, and its ability to provide detailed washout patterns. Also, CEUS's intravascular nature and lower risk of adverse reactions make it a safer alternative for patients with renal impairment or those contraindicated for CT/MRI.