Correlation between environmental factors and pediatric respiratory disease visits in a central hospital of Shanghai
10.16835/j.cnki.1000-9817.2025135
- VernacularTitle:上海市某中心医院儿科呼吸道疾病就诊与环境因素的相关性
- Author:
ZHOU Shuangshuang, CAI Yizhou, MIAO Xueqin, ZHANG Lili, ZHOU Yibin, HE Dandan, LIU Jie, HU Yanqi
1
Author Information
1. Dean s Office of Minhang Hospital, Fudan University, Shanghai (201199) , China
- Publication Type:Journal Article
- Keywords:
Respiratory tract diseases;
Ambulatory care;
Environment;
Models,statistical;
Child
- From:
Chinese Journal of School Health
2025;46(5):708-711
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation and lag effects of environmental factors on pediatric respiratory disease visits at hospital, so as to provide scientific basis for disease prediction and optimizing clinical diagnosis and treatment.
Methods:Data from 503 889 pediatric respiratory disease outpatient and emergency visits a central hospital in Minhang District of Shanghai between 2017 and 2019, along with concurrent meteorological data were collected. A distributed lag non-linear models (DLNM) was constructed to explore the specific relationship between pediatric respiratory disease consultations and various environmental factors and to quantify the cumulative lag effects of environmental factors on respiratory disease consultations.
Results:Among the environmental factors, temperature, fine particulate matter (PM 2.5 ), inhalable particulate matter (PM 10 ), nitrogen dioxide (NO 2), and sulfur dioxide (SO 2) were associated with pediatric respiratory disease visits. After adjusting for temperature, PM 2.5 and PM 10 concentrations did not show significant immediate or lag effects. The relative risk (RR) of pediatric respiratory disease visits increased with rising NO 2 concentrations. When NO 2 concentration ≥55 μg/m 3, significant immediate and lagged effects (lag 3, 5, and 7 days) were observed. The RR values were 1.05, 1.13, 1.17, and 1.21( P <0.05). The RR values showed an inverted “U” shaped relationship with SO 2 concentrations. When SO 2 concentration ≥5 μg/m 3, significant lagged effects (lag 3, 5, and 7 days) were observed. The RR values were 1.03 , 1.03, and 1.04 ( P <0.05).
Conclusion:High concentrations of NO 2 and SO 2 increase the risk of pediatric respiratory disease visits, with observable lag effects.