Systemic Lupus Erythematosus as a Dominant Disease in Traditional Chinese Medicine
10.13422/j.cnki.syfjx.20251496
- VernacularTitle:中医药临床优势病种探讨——系统性红斑狼疮
- Author:
Zihan WANG
1
;
Yanyu CHEN
1
;
Yong CUI
1
;
Qingwen TAO
1
;
Mei MO
2
;
Ke XUE
1
;
Xiaoxiao ZHANG
3
;
Yuan XU
1
Author Information
1. China-Japan Friendship Hospital，Beijing 100029，China
2. National Key Laboratory for The Innovation and Development of Modern TCM，Tianjin 300410，China
3. China Association of Chinese Medicine，Beijing 100029，China
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
dominant disease;
integrated traditional Chinese medicine （TCM） and Western medicine;
expert consensus
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(13):263-269
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus （SLE）， a refractory autoimmune disease， is among the dominant diseases where traditional Chinese medicine （TCM） shows advantages in the field of rheumatology and immunology. The China-Japan Friendship Hospital hosted the "46th Youth Salon on Dominant Diseases （Systemic Lupus Erythematosus）" organized by the China Association of Chinese Medicine， which led to a consensus on "the advantages， challenges， interdisciplinary approaches， and translational achievements of integrated TCM and Western medical approaches in the diagnosis and treatment of SLE." The diagnosis and treatment of SLE currently face several challenges， such as frequent misdiagnosis and missed diagnosis in the early stages， difficulty in achieving treatment targets， multiple side effects from pharmacotherapy， and the lack of management strategies for special populations， all of which hinder the fulfillment of the clinical needs of patients. Integrated TCM and Western medical approaches can improve clinical symptoms such as skin erythema， aversion to cold and cold limbs， fatigue， dry mouth， restlessness， and heat sensation in the palms and soles， thereby improving patients' quality of life. The approaches also help consolidate the efficacy of conventional Western medicine， slow disease progression， reduce relapse rates， address multi-organ involvement， and prevent or treat complications. Additionally， they enhance efficacy and reduce toxicity， prevent the side effects of Western medications， help reduce hormone use， and offer distinct advantages in the individualized intervention of special populations， contributing to the whole-process management of the disease. However， evidence-based medical support for this integrated approach remains limited， and the quality of available evidence is generally low. Common evaluation systems and modern research methodologies should be adopted to clarify the efficacy of TCM in SLE treatment. Efforts should be made to carry out high-quality evidence-based medical research， strengthen the development of fundamental and pharmacological research， and further explain the distinct advantages of TCM in the diagnosis and treatment of SLE. Future efforts should focus on advancing the integration of TCM and modern medicine， incorporating multi-omics technologies， individualized stratification， and other precision medicine concepts， in combination with artificial intelligence. Moreover， interdisciplinary collaboration should be promoted to utilize modern technology in exploring the essence of TCM theories and screening effective formulae， thereby comprehensively improving the diagnosis and treatment of SLE through integrated TCM and Western medical approaches.
