Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
10.3971/j.issn.1000-8578.2025.24.1084
- VernacularTitle:脊柱骨转移放疗的摆位误差及影响因素分析
- Author:
Wenhua QIN
1
;
Xin FENG
1
;
Zengzhou WANG
1
;
Shangnan CHU
2
;
Hong WANG
1
;
Shiyu WU
1
;
Cheng CHEN
1
;
Fukui HUAN
1
;
Bin LIANG
1
;
Tao ZHANG
1
Author Information
1. Department of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, China.
2. Department of Radiotherapy, Peking University Cancer Hospital and Beijing Institute of Cancer Prevention and Treatment, Key Laboratory of Pathogenesis and Transformation of Malignant Tumor, Ministry of Education, Beijing 100142, China.
- Publication Type:CLINICALRESEARCH
- Keywords:
Cone beam CT;
Spinal bone metastasis;
Radiotherapy;
Setup error;
Influencing factors;
BMI
- From:
Cancer Research on Prevention and Treatment
2025;52(5):400-404
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the setup error in patients with spinal bone metastasis who underwent radiotherapy under the guidance of kilovoltage cone-beam CT (KV-CBCT). Methods A total of 118 patients with spinal metastasis who underwent radiotherapy, including 17 cases of cervical spine, 62 cases of thoracic spine, and 39 cases of lumbar spine, were collected. KV-CBCT scans were performed using the linear accelerators from Elekta and Varian’s EDGE system. CBCT images were registered with reference CT images in the bone window mode. A total of 973 data were collected, and 3D linear errors were recorded. Results The patients with spinal bone metastasis were grouped by site, height, weight, and BMI. The P value of the patients grouped only by site was P<0.05, which was statistically significant. Conclusion When grouped by site in the 3D direction, the positioning effect of cervical spine is better than that of thoracic and lumbar spine. The positioning effect of the thoracic spine is better in the head and foot direction but worse in the left and right direction compared with that of the lumbar spine. Instead of extending or narrowing the margin according to the BMI of patients with spinal metastasis, the margin must be changed according to the site of spinal bone metastasis.
