Application of Thermal Tomography in Breast Cancer Screening
10.3971/j.issn.1000-8578.2025.24.1213
- VernacularTitle:热层析成像技术在乳腺癌筛查中的应用
- Author:
Kankan ZHAO
1
;
Bo CHEN
1
;
Wenliang LU
1
;
Yao CHENG
2
;
Hongmei ZHENG
3
;
Xinhong WU
3
;
Shengrong SUN
4
;
Ziming HUANG
1
Author Information
1. Department of Thyroid and Breast Surgery, Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China.
2. Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China.
3. Department of Breast Surgery, Hubei Cancer Hospital, Wuhan 430079, China.
4. Department of Thyroid and Breast Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
- Publication Type:CLINICALRESEARCH
- Keywords:
Thermal tomography;
Breast cancer;
Screening;
Ultrasound
- From:
Cancer Research on Prevention and Treatment
2025;52(5):388-392
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness of thermal tomography in breast cancer (BC) screening. Methods We conducted a general population-based BC screening in three regions of Hubei Province (Xiantao, Hongan, and Yangxin Districts). Participants underwent a questionnaire-based interview for baseline data collection. They then received a physical examination, thermal tomography, and ultrasound from doctors and technicians. We compared the efficacies, including sensitivity, specificity, and false-positive rates, of ultrasound and thermal tomography in BC screening. Results A total of 59 712 eligible women were included in this screening program. The BI-RADS 1, 2, 3, 4, and 5 accordance rates between the two screening methods were 0.9549, 0.8047, 0.9037, 0.3352, and 0, respectively. The overall accordance rate was 0.933 1. The kappa consistency results showed that the Cicchetti-Allison and Fleiss-Cohen kappa values were 0.7970 and 0.8583, respectively. Although the two methods had equal sensitivities, specificity was higher in thermal tomography than in ultrasound. The false-positive rate was lower in thermal tomography than in ultrasound. The area under the receiver operating characteristic (ROC) curve of thermal tomography was significantly larger than that of ultrasound. Conclusion The general consistency between thermal tomography and ultrasound in BC screening was high. Thermal tomography outperformed ultrasound in terms of specificity and diagnostic efficiency. Therefore, thermal tomography has a high application value for general population-based BC screening.
