Clinical Significance of BNP and NT-proBNP in Chronic Kidney Disease
- VernacularTitle:Бөөрний архаг өвчний үеийн натри хөөгч пептид: Эмнэлзүйн ач холбогдол
- Author:
Anudari I
1
;
Buyandelger J
1
;
Munkhzul D
2
;
Sodgerel B
1
Author Information
1. Institute of Medical Sciences of Mongolia
2. The Third State Central Hospital
- Publication Type:Review
- Keywords:
BNP;
NT-proBNP;
chronic kidney disease;
cardiovascular disease
- From:Mongolian Medical Sciences
2024;210(4):53-60
- CountryMongolia
- Language:Mongolian
-
Abstract:
Chronic kidney disease (CKD) is a global health issue characterized by a gradual loss of kidney
function over time. As the disease progresses, it leads to an increased risk of cardiovascular
complications, which are the leading cause of morbidity and mortality in CKD patients.
B-type natriuretic peptide (BNP) and its inactive fragment, N-terminal pro b-type natriuretic
peptide (NT-proBNP), are biomarkers widely used in the diagnosis and management of heart
failure. Their role in CKD, however, is complex due to the overlapping pathophysiological
mechanisms between cardiac and renal dysfunctions. This literature review aims to explore
the diagnostic and prognostic value of BNP and NT-proBNP in patients with CKD, highlighting
their clinical relevance, the impact of renal function on their levels, and potential therapeutic
implications. The review focuses on studies published in the last decade, examining the
clinical applications, outcomes, and challenges associated with using BNP and NT-proBNP
as biomarkers in CKD patients.
- Full text:2025060517323082098MMS-2024-210(4)-53-60.pdf
