A study risk factor of pregnancy and birth complications associated with group B streptococcus colonization
- VernacularTitle:Жирэмслэлт, төрөлтийн хүндрэлийн эрсдэлийг Б бүлгийн стрептококкийн колонизацитай холбон судалсан нь
- Author:
Wurihan A
1
,
2
;
Damdindorj B
1
;
Jargalsaikhan B
1
Author Information
1. Mongolian National University of Medical Sciences
2. Affiliated Hospital of Chifeng University, Inner Mongolia, China
- Publication Type:Journal Article
- Keywords:
premature rupture of amniotic membrane;
chorionamniotit;
fetal distress syndrome
- From:Mongolian Medical Sciences
2024;210(4):26-34
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Group B Streptococcus (GBS), also referred as Streptococcus agalactiae, is one of the leading
causes of life-threatening invasive diseases such as bacteremia, meningitis, pneumonia and
urinary tract infection in pregnant women and neonates. Rates of GBS colonization vary by
regions, but large-sample studies on maternal GBS status are limited in southern China. As
a result, the prevalence of GBS among pregnant women and its associated risk factors and
the efficacy of intrapartum antibiotic prophylaxis (IAP) intervention in preventing adverse
pregnancy and neonatal outcomes remain poorly understood in Inner Mongolia, China.
Objective:This study was to investigate the colonization rate of Group B Streptococcus (GBS) during
pregnancy, and to evaluate the influence of GBS colonization on pregnancy and birth
outcomes in Inner Mongolian women, China
Material and Method:A prospective case control study. Setting Data of 981 pregnant women from 2023 were
collected from the Affiliated Hospital of Chifeng University, Inner Mongolia, China.
Primary outcome measures:The incidence rates of GBS colonization and premature
rupture of membranes, meconium-stained amniotic fluid, chorioamnionitis, postpartum
hemorrhage and fetal distress.
Results:Of the 981 pregnant women included in this study, 327 developed GBS colonization.
The occurrence of GBS colonization not varied among different ethnic groups. Our data
revealed that premature rupture of membranes (PROM) meconium-stained amniotic fluid,
chorioamnionitis, postpartum hemorrhage and fetal distress were more common in pregnant
women colonized with GBS than in pregnant women not colonized with GBS. The incidence
for PROM, meconium stained amniotic fluid, chorioamnionitis, postpartum hemorrhage and
fetal distress in infants of pregnant women colonized with GBS was 19.7% (OR=1.5; 95% CI,
0.981 to1.964), 8.3% (OR=2.2; 95% CI, 1.320 to 3.653), 11.3%, (OR= 1.6; 95% CI, 0.324
to 0.77), 8.2% (OR=1.0; 95% CI, 0.99-2.112), 4.1% (OR=6.54; 95% CI, 2.887 to14.805)
respectively.
Conclusion:Maternal GBS colonization, longer duration of membrane rupture were all
major risk factors associated with GBS colonization in Inner Mongolian Chinese women.
Pregnant women colonized with GBS were more predisposed to PROM, meconium-stained
amniotic fluid, chorioamnionitis and postpartum hemorrhage. Infant GBS colonization was
associated with increased risk of fetal distress.
- Full text:2025060517201636645MMS-2024-210(4)-26-34.pdf
