Determining antibiotic susceptibility and multidrug resistance of the pathogens isolated from wound infection
- VernacularTitle:Шархны халдвар үүсгэгчийн антибиотик мэдрэг чанарыг тодорхойлон, олон эмэнд тэсвэржилтийг илрүүлсэн нь
- Author:
Altantsetseg D
1
;
Tserendulam B
1
;
Nomiundari E
2
;
Lkhagvadorj D
2
;
Gerelmaa Ts
2
;
Undarmaa S
1
;
Dagvadorj Ts
2
Author Information
1. Ach Medical University
2. National Center for Communicable Diseases
- Publication Type:Journal Article
- Keywords:
Antimicrobial Resistance (AMR);
Carbapenem-Resistant Klebsiella pneumonia (CPK);
Extended spectrum beta-lactamase (ESBL);
Methicillin-resistant Staphylococcus aureus (MRSA);
Multidrug Resistance in Bacteria (MDR);
Vancomycin-Resistant Enterococcus (VRE)
- From:Mongolian Medical Sciences
2024;210(4):3-8
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:Antimicrobial Resistance (AMR) has emerged as a significant public health and economic
issue worldwide, affecting both developed and developing countries. Our research has been
motivated by the increasing prevalence of carbapenem-resistant P. aeruginosa, A.baumannii,
and K. pneumonia in recent years.
Goal:To determine antibiotic susceptibility of the pathogens isolated from wound infection and to
detect its multidrug resistance.
Material and Method:Samples were collected from patients with wound infections. Pathogens were identified
by using the traditional culture methods and the API system with serotypes determined
phenotypically. Antibiotic susceptibility was assessed using the disk diffusion method and
the MIC to analyse antibiotic resistance.
Results:In the study, among 11,221 recorded cases of wound infections in 2023, bacterial pathogens
were detected and identified at the species level in 10,339 cases (92.1%).
For identification results showed that A. baummannii were detected from 138 cases (1.3%),
216 cases (2.08%) of Ps. aeruginosa, 5 cases (0.04%) of B. cepacia, 1,383 cases (13.4%)
of Enterobacteriaceae, 205 cases (2.0%) of Enterococcus spp., 8,329 cases (80.5%) of
Staphylococcus spp., and 63 cases (0.6%) of Streptococcus spp.
Antibiotic susceptibility of these bacteria was assessed and determined multidrug
resistance. We found the followings: For A. baumannii were resistant with MDR in 68 cases
(49.3%), MRSA in 4,243 cases (51.1%), MDRSta. aureus in 1,805 cases (29.4%), VRE in
34 cases (16.5%), ESBL in 4.6%, KPC in 26 cases (11.1%), FRNF in 24 cases (11.6%), and
CRPA in 13 cases (6.3%).
Conclusion:
1. Of all wound infections reported in 2023 in 92.1% there were detected pathogenic bacteria,
of which S.aureus were in 80.5% and E. coli was in 13.4%
2. 60.7% of the pathogenic bacteria detected in wound infections were multidrug-resistant,
with MRSA accounting for 51.1% and MDR A.baumannii accounting for 49.3%, indicating
high antimicrobial resistance(AMR).
- Full text:2025060517041418744MMS-2024-210(4)-3-8.pdf
