Does air pollution affect liver disease?
- VernacularTitle:Агаарын бохирдол элэгний эмгэгт нөлөөлдөг үү?
- Author:
Bolor B
1
;
Enkhjargal A
2
,
3
;
Burmaajav B
3
Author Information
1. National Center for Public Health
2. World Bank funded Covid19- project implementation unit
3. Ach Medical University
- Publication Type:Lectures
- Keywords:
air pollution;
NAFLD;
liver cirrhosis prevalence;
adults
- From:Mongolian Medical Sciences
2024;207(1):52-59
- CountryMongolia
- Language:Mongolian
-
Abstract:
Liver disease accounts for approximately 2 million deaths per year worldwide and is responsible for
4% of all deaths. Acute hepatitis accounts for a smaller amount of mortality, with complications from
cirrhosis and other chronic liver diseases being the main causes of death. It is mostly brought on
by nonalcoholic liver disease, alcohol abuse, infections (chronic hepatitis B and C viruses), and air
pollution.
In the last 10 years, the number of deaths caused by hepatocellular carcinoma has been continuously
increasing in Mongolia, and it ranks first in the world in terms of deaths caused by hepatocellular
carcinoma per 100,000 population, which is 8 times higher than the world average.
Mongolia is one of the most polluted countries in the world. Globally it is estimated that 9 out of 10
breathe polluted air and about 7 million deaths are attributed to air pollution. Studies on epidemiology
have found an association between ambient air pollution and some liver diseases, including cirrhosis,
liver cancer, and fatty liver disease related to metabolic disorders. This is an issue with global health.
Exposure to PM2.5 is linked to the development of inflammation, which may be a major risk factor
in the advancement of non-alcoholic fatty liver disease. According to the literature review, exposure
to PM is associated with systemic inflammation, a rise in plasma triglycerides, LDL and VLDL, pro
inflammatory cytokines, and insulin resistance.
Many epidemiological and ecological studies were done in Mongolia on air pollution and health.
However, it is still not clear how much ambient air pollution can cause cirrhosis and non-alcoholic fatty
liver disease incidence in Mongolia.
- Full text:2025060517434020368MMS-2024-207(1)-52-59.pdf
