Evaluation of some changes in liver function in patients with alcohol use disorder
- VernacularTitle:Архинд донтох эмгэгтэй үйлчлүүлэгчдийн элэгний үйл ажиллагааны зарим өөрчлөлтийг үнэлсэн дүн
- Author:
Udmaral B
1
;
Byambajargal D
1
;
Pagmadulam B
1
;
Oyundelger M
1
;
Zoljargal S
2
;
Oyunchimeg D
2
;
Erdenebat N
2
Author Information
1. Department of Medicine, Etugen University
2. Addictology Center
- Publication Type:Journal Article
- Keywords:
alcohol dependence;
liver function;
Michigan test;
ALT;
AST
- From:
Diagnosis
2025;112(1):75-79
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:To evaluate changes in liver function in patients with alcohol use disorder and propose preventive measures.
Methods:In this study, 118 people were examined between January 2024 to December 2024. Results were analyzed SPSS.
Result:The mean subject age was 48.6± 10.3 years, male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, ALT 86.7 ± 93.8 (U/L), AST 89.3±82.8 (U/L), GGT 213.8±252.3 (U/L). A statistically
significant correlation was found between AST and ALT levels (R² = 0.562). However, no significant correlation was observed between body mass index (BMI) and blood glucose levels (R² = 0.002). The AST/ALT ratio was also statistically significant (p = 0.0001).
Conclusion:Excessive alcohol consumption increases the levels of liver enzymes AST 89.3 ± 82.8 (U/L), ALT 86.7
± 93.8 (U/L), and GGT 213.8 ± 252.3 (U/L), leading to increased liver cell damage. Therefore, it is necessary to reduce alcohol consumption and implement preventive measures.
- Full text:2025053015112736347Diagnosis-2025-112(1)-75-79.pdf
