Identification of some risk factors associated with Ineffective oesophageal motility
- VernacularTitle:Улаан хоолойн үр дүнгүй гүрвэлзэх эмгэгийн зарим эрсдэлт хүчин зүйлийг судалсан дүн
- Author:
Amarjargal B
1
;
Oyuntugs B
2
;
Bayarmaa N
3
;
Sarantuya G
3
Author Information
1. Department of Gastroenterology and Endoscopy, Intermed hospital
2. Department of Endocrinology, School of Medicine, MNUMS
3. Department of Gastroenterology, School of Medicine, MNUMS
- Publication Type:Journal Article
- Keywords:
High-resolution oesophageal manometry;
Hiatal hernia;
Obesity
- From:
Mongolian Journal of Health Sciences
2025;86(2):149-153
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Esophageal cancer ranks as the fourth most prevalent malignancy in Mongolia. Among esophageal disorders,
gastroesophageal reflux disease (GERD) accounts for 55% of cases, while esophageal motility disorders constitute
40%. Enhancing the diagnosis and management of esophageal disorders, alongside preventative strategies for esophageal
cancer, necessitates a comprehensive understanding and widespread clinical application of esophageal functional assessment.
However, epidemiological data and classification of esophageal motility disorders remain scarce in Mongolia,
highlighting the necessity of this investigation.
Aim:to identify specific risk factors associated with ineffective esophageal motility (IEM)
Materials and Methods:This study was performed an analytical case-control design and was conducted at Intermed
Hospital. A total of 702 HRM test results from patients attending the Gastroenterology and Endoscopy Center’s outpatient
department, Intermed hospital Participants diagnosed with IEM based on HRM findings were assigned to the case group,
while individuals with esophageal normal motility disorders were designated as the control group at a 1:2 ratio.
Results:A total of 612 participants aged 21–80 years were included in this study of whom 57.8% (n=354) were female
and 42.2% (n=258) were male, with a mean age of 51.1±12.7 years. The prevalence of IEM demonstrated a statistically
significant increase in the 60–69 and ≥70 age groups compared to the control group (p<0.000). Participants diagnosed
with IEM exhibited a mean lower esophageal sphincter (LES) pressure of 329.61±246 mmHg and a mean complete liquid
bolus transit rate of 46.88±22.7%, both of which were significantly lower than those observed in the control group
(p=0.000). Furthermore, the incidence of IEM was found to increase in correlation with the severity of hiatal hernia, as
classified by both endoscopic and manometric criteria, demonstrating statistical significance (p=0.000).
Conclusion:IEM is more prevalent among elderly individuals and increases in incidence with the progression of hiatal
hernia size. In cases of IEM, esophageal bolus transit is significantly delayed, and lower esophageal sphincter pressure
is diminished. Further studies are warranted to elucidate additional risk factors contributing to ineffective esophageal
motility.
- Full text:202505291319429926149-153.pdf
