Estimated glomerular filtration rate in alcohol use disorder people
- VernacularTitle:Архинд донтох эмгэгтэй үйлчлүүлэгчдийн бөөрний үйл ажиллагааг үнэлсэн нь
- Author:
Khorolgarav A
1
;
Narantsatsral D
1
;
Oyundelger M
1
;
Zoljargal S
2
;
Oyunchimeg D
2
;
Erdenebat N
2
Author Information
1. School of Medicine, Etugen University
2. Addictology Center
- Publication Type:Journal Article
- Keywords:
estimated Glomerular filtration rate;
alcohol use disorder
- From:
Diagnosis
2025;112(1):5-9
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:The purpose of this study is to evaluate serum creatinine as a marker of estimated glomerular filtration rate (eGFR) in alcohol use disorder people, and to determine correlation between mean arterial pressure (MAP) and eGFR in chronic kidney disease classification level.
Methods:In this study, 118 people were examined 2024. We measured serum creatinine based GFR using the Cockroft Gault formula. Biochemical analysis and serum creatinine were evaluated using a fully automatic analyzer (GOLSITE, China). Statistical results were analyzed SPSS.
Result:The mean subject age was 48.6±10.3, BMI 25.3±3.7 and male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, eGFR 94±28 ml/ min/1.73m2, and mean arterial pressure was significantly correlated with estimated glomerular filtration rate (P<0.05) and no difference between male and female recipients. Mean eGFR was calculated into 4 groups of 10-year intervals, that eGFR was decreased significantly with age groups. For the alcohol dependence stages of the Michigan Test, the mean eGFR was stage 1 is 112 ml/min/1.73m2, stage 2 is 89 ml/min/1.73m2, stage 3 is 97 ml/min/1.73m2 and there is not statistically significant correlation between Michigan test scores and eGFR.
Conclusion:According to our research, one of the optimal methods for assessing kidney function is the creatinine-based CKD calculation method, and long-term excessive alcohol consumption is a risk factor for CKD, as well as one of the main causes of death due to hypertension and cardiovascular disease.
- Full text:2025052723315038389Diagnosis-2025-112(1)-5-9.pdf
