Associations of secondary risk factors of non-communicable diseases
- VernacularTitle:Халдварт бус өвчний хоёрдогч эрсдэлт хүчин зүйлсийн хамаарал
- Author:
Khangai E
1
;
Batzorig B
2
;
Narantuya D
3
;
Enkhtur Ya
4
;
Oyuntugs B
5
;
Bayarbold Dangaa
6
;
Oyunsuren E
6
Author Information
1. Department of Family Medicine, SOM , MNUMS
2. Department of Epidemiology and Biostatistics, SPH, MNUMS
3. State Central Third Hospital
4. School of Medicine, MNUMS
5. Department of Endocrinology, SOM, MNUMS
6. Ministry of Health
- Publication Type:Journal Article
- From:
Diagnosis
2024;111(4):51-58
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Obesity and metabolic disorders are significant contributors to hypertension and cardiovascular disease
(CVD). While body mass index (BMI) and waist circumference are known to be associated with systolic blood pressure (SBP), the interplay between adiposity, glucose levels, triglycerides, and SBP is
not fully understood. This study aims to investigate the relationships between BMI, waist circumference, glucose, triglycerides, and SBP in a large population-based cohort.
Methods:A cross-sectional analysis was conducted on [insert total number] participants with complete data on BMI, waist circumference, blood pressure, glucose, and triglycerides. Descriptive statistics, ANOVA, Pearson correlations, mediation analysis, and multiple regression were used to explore the associations between variables. The moderation effect of glucose on the BMI-SBP relationship
was examined using an interaction term in the regression model.
Results:The mean age of the study population was 44.3 ± 15.2 years. The mean BMI was 26.7 ± 4.9 kg/m², and 22.7% of participants were classified as obese. Central obesity, measured by waist
circumference, was prevalent in 55.9% of the population. BMI, waist circumference, glucose, and triglycerides were significantly associated with SBP (p < 0.0001). Mediation analysis showed that waist circumference partially mediated the effect of BMI on SBP. The interaction term for BMI and
glucose was significant (β = 0.32, p < 0.05), indicating that glucose levels moderated the relationship between BMI and SBP, with higher glucose levels amplifying the hypertensive effect of BMI.
Conclusion:This study highlights the complex interplay between BMI, waist circumference, glucose, triglycerides, and SBP. Waist circumference partially mediates the effect of BMI on SBP, and glucose levels moderate this relationship, amplifying the impact of obesity on blood pressure.
- Full text:2025052723031975796Diagnosis-2024-111(4)-51-58.pdf
