Results of a Geographical Study of Hematology Parameters in Mongolians
- VernacularTitle:Монгол хүний цусны шинжилгээний үзүүлэлтүүдийг газарзүйн бүсчлэлээр судалсан дүн
- Author:
Urangoo T
1
,
2
;
Otgonbat A
1
;
Purevjal O
1
Author Information
1. Department of hematology, School of Medicine, MNUMS
2. Department of clinical laboratory, Mongolia-Japan Hospital, MNUMS
- Publication Type:Journal Article
- Keywords:
Platelet;
White blood cell;
Age;
Regional classification
- From:
Mongolian Journal of Health Sciences
2025;86(2):91-96
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Reference values for a complete blood count (CBC) can vary due to multiple factors, including geographical
location, environmental influences, nutrition, genetic characteristics, lifestyle, and the physical-chemical properties of
the blood. Mongolia’s high-altitude geography (an average of 1,580 meters above sea level) reduces oxygen supply and
activates hematopoiesis through the body’s physiological adaptation mechanisms. As a result, the number of red blood
cells, hemoglobin, and hematocrit levels tend to increase, as studied by researchers Ch. Sharav and A. Ulziikhutag. Considering
the unique geographical regions of Mongolia (urban, rural, steppe, desert, and high mountain areas), studying the
physiological blood parameters of the population and identifying regional differences are crucial for improving diagnostic
accuracy and the reliability of clinical assessments, which form the basis for conducting this study.
Aim:Select a healthy group from the population that participated in the ‘National Preventive Screening and Early Diagnosis
Program’ for preventing and early detecting infectious and non-infectious diseases based on age, gender, and health
risks. Establish reference values for comprehensive blood test indicators by geographical location.
Materials and Methods:In Mongolia, from 2022 to May 2023, a comprehensive blood analysis was conducted on 7,301
individuals aged 18 and above who participated in the ‘National Preventive Screening and Early Diagnosis Program’
aimed at preventing and early detecting infectious and non-infectious diseases based on age, gender, and health risks. The
analysis included red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean
corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), white blood cell count (WBC),
and platelet count (PLT) in relation to their geographical location. The study results were calculated using IBM SPSS (20)
software. Statistical significance was considered at p<0.05.
Results:In our study, 7,301 people aged 18-87 participated, of whom 36.4% (2,644) were male and 63.6% (4,657) were
female. The average age was 30.2±0.2 years for men and 35.1±0.1 years for women. Among them, there were 1,764 males
and 1,774 females aged 18-30, 603 males and 2,069 females aged 31-45, 199 males and 670 females aged 46-60, and
78 males and 144 females over 61 years old. A total of 26.6% (1,944) of the study participants were from Ulaanbaatar,
12.75% (931) from the western region, 10.12% (739) from the eastern region, 33.18% (2,423) from the Khangai region,
and 17.31% (1,264) from the central region. In the Ulaanbaatar region, HGB, HCT, MCV, MCH, and WBC increased
with age, while PLT showed a tendency to decrease. Differences in HGB, HCT, MCV, MCH, MCHC, WBC, and PLT
indicators were observed between the western, eastern, Khangai, and central regions depending on the area (p<0.05).
Conclusion:Statistically significant differences in blood parameters were observed across different regions of Mongolia,
indicating the necessity of establishing reference values for blood tests that reflect the influences of geographical location,
lifestyle, and environmental factors (p<0.05).
- Full text:202505271648146724291-96.pdf
