Risk of cardiovascular disease in Mongolian patients with rheumatoid arthritis
- VernacularTitle:Ревматоид артриттай хүмүүст зүрх судасны эрсдэлийг тодорхойлсон дүн
- Author:
Anu G
1
;
Tsolmon D
1
;
Devshil Z
1
;
Altanzul B
1
;
Chingerel Kh
1
;
Zulgerel D
1
Author Information
1. Department of Rheumatology, School of Medicine, MNUMS
- Publication Type:Journal Article
- Keywords:
Criteria;
Activity;
Biomarker;
Factor;
Inflammation
- From:
Mongolian Journal of Health Sciences
2025;85(1):115-119
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Patients with rheumatoid arthritis are at increased risk of developing cardiovascular disease. In Mongolia,
the registration of inflammatory diseases is increasing every year, and cardiovascular diseases are the leading cause of
death.
Aim:We aimed to determine the degree of cardiovascular risk and its correlation in people with rheumatoid arthritis.
Materials and Methods: The study was conducted in a cross-sectional study design with 64 patients with rheumatoid
arthritis between May and November 2024. Cardiovascular risk was assessed using mSCORE and the World Health Organization (WHO) cardiovascular Risk Table. We received ethical approval to begin the research at the MNUMS meeting
on May 17, 2024 (No. 2024/3-05).
Results:The average age of the participants was 55.2±9.7 years, and the average duration since being diagnosed with RA
was 9.8±8.0 years. Among the participants, 82.8% (n=53) were female, and 17.2% (n=11) were male. The mean WHO
risk index was 10.25±11, while the mean mSCORE risk index was 2.9±4 (p=0.001). There was a significant difference in
mSCORE scores between the 40-55 and 56-65 age groups (p<0.001). In contrast, the mSCORE risk assessment showed
that 15.6% (n=10) had high risk, and 6.3% (n=4) had very high risk. Among the parameters of inflammatory biomarkers,
CRP (OR=0.05, r=0.35, 95% CI 0.9-3.2, p=0.004) has a statistically significant difference and positive correlation, and
HDL-C (OR=2.3, r=-0.25, 95% CI 2.9- 10.0, p<0.0001) was significantly different and negatively correlated.
Conclusion:A total of 64 participants participated in our study, and according to the WHO assessment, 17.2% were at
high or very high risk of developing cardiovascular disease in the next 10 years, and according to the mSCORE, 21.9%
were at high or very high risk of developing cardiovascular disease. Although the degree of disease activity was not significantly associated with cardiovascular risk, the inflammatory biomarker C-reactive protein was statistically significantly different or positively associated with cardiovascular risk assessment.
- Full text:2025052715111616081115-119.pdf
